Annual best paper award

4th Joint Workshop on Computer/Robot Assisted Surgery.

Annual Best Paper Award:

Neurophysiology guided single cell optical surgery. Averna A, Bisio M, Pruzzo G, Chiappalone M, Bonifazi P and Difato F.

Imaging of mouse experimental melanoma in vivo and ex vivo by combination of confocal and nonlinear microscopy

Item Link Read more
0.0/5 rating (0 votes)
  • 20 March 2012
  • File size: 1.20 MB
  • Downloaded: 675

We investigated possibilities of confocal reflectance and  fluorescence microscopy in combination with SHG and two-photon autofluorescence imaging for the examination of experimental melanoma tissues in vivo, in mice under general anesthesia, and  ex vivo on freshly harvested specimens. Our approach facilitated  the examination of interrelationships between functional and  morphological aspects based on optical properties of the tissues. It proved to be suitable for describing the tumor structure and  documenting changes due to the effect of microwave hyperthermia treatment, such as modification of the collagen fiber network together with the other tissues. The results showed that the proposed approach could be suitable for a direct evaluation of  clinical interventions.